Reportlinker.com has introduced a new market research report titled Proteomics – Technologies, Markets and Companies that describes and studies the proteomic technologies, which play a key role in molecular diagnostics, drug discovery and practice of medicine.
The technologies, which are commonly used today, are protein analysis by mass spectrometry and 2D gel electrophoresis. Improvement in reliability and throughput of peptide mapping could be obtained by multi-dimensional liquid chromatography or mass spectrometry with micro-analytical protein characterization. MALDI-MS or Matrix-Assisted Laser Desorption Mass Spectrometry is now a commonly used method for determining bio-molecules such as proteins and peptides. Yeast two-hybrid system, which is used for evaluating protein-protein interactions, is a part of Functional Proteomics technologies.
To establish a proteomics platform within the industrial set up would involve implementing a succession of robotic systems, which would permit a high-throughput approach for identification and analysis of the variations seen on 2D electrophoresis gels. Protein chips have also become a useful tool. Proteomic technologies are being combined in drug discovery processes. Toxico-proteomics or the study of protein expression for knowing and understanding the toxic events is also a significant use of proteomics technology in pre-clinical drug safety. Bioinformatics is vital to study the huge amount of data obtained from proteomics and genomics.
Proteomics helps understand the patho-mechanisms of diseases. An investigation of various gene expression levels in both diseased and healthy tissues by proteomic methods is equally important as the detection of polymorphisms and mutations at the genomic level and may even be of greater benefit while charting out a rational therapy plan. In the future, proteomics will dominate the medical field, which would be a combination of both therapeutics and diagnostics. It would be used on neurological disorders (neuro-proteomics) and on cancer (onco-proteomics).
An analysis of the proteomic technologies for the year 2010, along with projections up to 2020 are given in the report. The report also includes information about the basics of proteomics, protein biochip technology, pharmaceutical applications of proteomics, use of proteomics in health care and the future of proteomics.