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HeartFlow to Present Seven-Year Data on AI-Enabled Heart Care Solutions at TCT Conference

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HeartFlow, Inc.Oct 15 2024Reviewed

HeartFlow, the global leader in non-invasive artificial intelligence (AI) heart care solutions, today announced it will present seven-year data from the ADVANCE-DK study, a subset from the larger ADVANCE Registry, which evaluated utility and clinical outcomes of HeartFlow’s AI-enabled FFR_CT and Plaque Analysis in clinically stable, symptomatic patients with coronary artery disease (CAD). Data from the ADVANCE-DK study and other clinical studies will be presented at the 36th annual Transcatheter Cardiovascular Therapeutics^® (TCT) conference, which will take place October 27-30, 2024 in Washington, D.C.

“The ADVANCE registry helps us better understand whether more complete revascularization, as defined by FFR_CT, is associated with improved long-term cardiovascular outcomes,” said Campbell Rogers, M.D., F.A.C.C., Chief Medical Officer of HeartFlow. “Three-year data from this registry confirmed that patients with both abnormal FFR_CT and high plaque burden had two-and-a-half to three times greater risk of adverse cardiac events compared to patients with only abnormal FFR_CT or high plaque volume. We are excited to present seven-year data and build on our body of evidence demonstrating FFR_CT and AI-enabled plaque assessment as non-invasive approaches which can help physicians better quantify CAD risk in their patients.”

At TCT, HeartFlow will also present:

Late-breaking data evaluating the capacity of FFR_CT and coronary computed tomography angiography (CCTA) to rule out significant lesions in high-risk non-ST elevation acute coronary syndromes (NSTE-ACS).
Data from FUTURE-AS, an international, prospective, multicenter registry of patients with severe aortic stenosis (AS) referred for transcatheter aortic valve replacement (TAVR) being assessed for CAD with CCTA and FFR_CT.
New data from FASTTRACK-CABG, a single-arm, multicenter, prospective study assessing safety and feasibility of bypass surgery in patients with complex CAD solely based on CCTA combined with FFR_CT.
Data highlighting the value for pre-procedural planning of combining FFR_CT, virtual percutaneous coronary intervention (PCI), and myocardial mass.
Analysis of initial FFR_CT-based virtual PCI for pre-procedural planning in the U.S.

Details of each presentation are as follows:

Title: Completeness of Revascularization by FFR_CT and Long-term Prognosis in Stable Angina: A Seven-Year Follow-up of the ADVANCE-DK Registry
Presenter: Kristian Taekker Madsen, M.D., Ph.D.
Date: Sunday, October 27, 2024
Time: 7:30-8:45 AM EDT
Session: TCT WorldLink Forum: Best Global Research in Coronary Imaging
Location: Presentation Theater 3, Innovation & Exhibit Hall (Halls A-C)

Title: TCT 288: Comparative Analysis of FFR Derived From CCTA, Murray Law-Based Quantitative Flow Ratio and Quantitative Flow Ratio at Sequential Side Branches in Patients With Complex CAD: Insights From the FASTTRACK CABG Study
Presenter: Kotaro Miyashita, M.D.
Date: Sunday, October 27, 2024
Time: 9:00-9:50 AM EDT
Session: Moderated Abstracts Station 2
Location: Innovation & Exhibit Hall (Halls A-C)

Title: TCT 172: Usefulness of FFR_CT to Exclude Hemodynamically Significant Lesions in High-Risk NSTE-ACS
Presenter: Georgios Tzimas, M.D.
Date: Monday, October 28, 2024
Time: 4:00-5:30 PM EDT
Session: Moderated Abstracts Station 2
Location: Innovation & Exhibit Hall (Halls A-C)

Title: TCT 830: Feasibility and Utility of Anatomical and Physiological Evaluation of Coronary Disease With Cardiac CT in Severe Aortic Stenosis (FUTURE-AS Registry)
Presenters: Abdul Rahman Ihdayhid, M.D., Ph.D.
Moderators: Philippe PM Garot, M.D., Marie-France Poulin, M.D.
Date: Tuesday, October 29, 2024
Time: 8:00-9:00 AM EDT
Session: TAVR and CAD - 1
Location: Moderated Abstracts Station 5, Innovation & Exhibit Hall (Halls A-C)

Title: TCT 221: Coronary Computed Tomography Angiography-Guided Bifurcation Percutaneous Coronary Intervention: Role of FFR_CT Virtual PCI and Myocardial Mass for Pre-Procedural Planning
Presenters: Pedro Carvalho, M.D.
Moderators: Hector M. Garcia-Garcia, M.D., Ph.D., John J. Lopez, M.D.
Date: Tuesday, October 29, 2024
Time: 2:00-3:00 PM EDT
Session: Anatomy-derived Coronary Physiology – 2
Location: Moderated Abstracts Station 2, Innovation & Exhibit Hall (Halls A-C)

Title: TCT 96: Coronary Computed Tomography Angiography for Percutaneous Coronary Intervention: Initial US Experience With FFR_CT-Based Virtual PCI for Pre-Procedural Planning
Presenters: Pedro Carvalho, M.D.
Moderators: Louis A. Cannon, M.D., Christopher Irobunda. M.D.
Date: Wednesday, October 30, 2024
Time: 9:00-9:56 AM EDT
Session: Novel Percutaneous Techniques
Location: Moderated Abstracts Station 6, Innovation & Exhibit Hall (Halls A-C)

Heartflow invites attendees to a lunch symposium, “Utilizing Coronary CTA & HeartFlow AI to Non-Invasively Assess Anatomy, Physiology and Plaque,” led by a panel of well-respected physicians including Ziad A. Ali, M.D., Suzanne J. Baron, M.D., Nick Curzen, M.D., Jimmy Lee Kerrigan, M.D. and Akiko Maehara, M.D. The symposium will take place on Tuesday, October 29, 2024, from 12:30-1:30 PM EDT in the FDA Theater, Innovation & Exhibit Hall (Halls A-C).

Source:

HeartFlow, Inc.

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